Entabeni Epilepsy Laboratory
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Temporal Lobe Epilepsy

Removal of a portion of the temporal lobe (temporal lobectomy) Temporal Lobe
is the most common and most successful type of epilepsy surgery.  In most cases, a modest portion of the brain is removed, measuring approximately 4 cm in length.  The temporal lobes are important in memory and emotion.  In addition, the upper and back part of the "language-dominant" temporal lobe, which is on the left in nearly all right-handed people and most left-handed people, is vital for language comprehension.  The preoperative assessment ensures that removal of the area causing seizures will not disrupt memory or language functions.  However, when surgery is performed on the left side, there is often a slight reduction in memory functions after the operation.  In contrast, after right-sided (nondominant) temporal lobectomy, memory functions often improve slightly. 

The success rate for seizure control in temporal lobectomy is variable:
  • 55% to 70% of patients are free of seizures that impair consciousness or cause abnormal movements, but auras can persist in some;
  • 20% to 25% of patients have some seizures but are significantly improved (greater than 85% reduction of complex partial and tonic-clonic seizures); and
  • 10% to 15% of patients have no worthwhile improvement.
Therefore more than 85% of patients will enjoy a marked improvement in seizure control.  Most will be on less medication after surgery.  Approximately 20% of persons who are seizure-free are able eventually to discontinue anti-epileptic medication.

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