Entabeni Epilepsy Laboratory
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Investigations
Temporal Lobe Epilepsy
Lesional Epilepsy
Nonlesional Focal Epilepsy
Generalised Epilepsy
Hemispheric Syndromes

Lesional Epilepsy

Lesional epilepsy is characterized by an epileptogenic Defined Lesion
(epilepsy inducing) structural lesion, which might include a malformation of blood vessels, a tumor or an area of abnormal brain tissue. The surgical approach depends on the correlation or link between the EEG and brain scan findings.  Well defined lesions in non-vital brain tissue can be completely removed, with the post-operative seizure-free rate reaching as high as 70% to 90%.  In some cases however, the microscopic abnormal brain cells extend beyond the MRI-defined lesion (e.g. cortical dysplasia), and this might result in surgical failure.  Long duration of epilepsy suggests the possibility of a more-widely-distributed epileptogenic area or network, and intracranial (below the skull directly onto the brain tissue) electrodes can be used to more accurately define the abnormal area.
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